An antisense strategy and network pharmacology approach in zebrafish models to identify novel targets for pharmacoresistant epilepsy KU Leuven
The discovery of novel drug targets is a significant challenge in drug development. Specifically, in the field of epilepsy still 30% of patients do not experience adequate seizure control with currently available medications, which highlights the need to look for new approaches capable of defining specific molecular targets that could be used to identify novel anti-epileptic drugs (AEDs). Network-based strategies in drug discovery and ...