Role of peroxisomes for the homeostasis of mammalian cells and elucidation of the pathogenesis of peroxisomal diseases. KU Leuven
The general research goal of Prof. Myriam Baes is to decipher the role of peroxisomes in different mammalian tissues and cell types. Concurrently, her investigations aim to shed light on the pathogenesis of diseases caused by primary or secondary peroxisomal dysfunction.
We have generated and characterized multiple mouse models with peroxisome deficiencies, including the first mouse model (Pex5-/-) for Zellweger syndrome, followed by ...