Publications
Selection of egg peptide biomarkers in processed food products by high resolution mass spectrometry Research Institute for Agriculture, Fisheries and Food Flanders Institute for Biotechnology Ghent University
High-resolution mass spectrometry-based selection of peanut peptide biomarkers considering food processing and market type variation. Flanders Institute for Biotechnology Research Institute for Agriculture, Fisheries and Food Ghent University
Prediction models and peptide profiling in the assessment of the implant ation potential of early embryos KU Leuven
Alzheimer's disease cerebrospinal fluid biomarker in cognitively normal subjects Vrije Universiteit Brussel University of Antwerp
In a large multicentre sample of cognitively normal subjects, as a function of age, gender and APOE genotype, we studied the frequency of abnormal cerebrospinal fluid levels of Alzheimer's disease biomarkers including: total tau, phosphorylated tau and amyloid-β1-42. Fifteen cohorts from 12 different centres with either enzyme-linked immunosorbent assays or Luminex® measurements were selected for this study. Each centre sent nine new ...
Selecting Aβ isoforms for an Alzheimer's disease cerebrospinal fluid biomarker panel Vrije Universiteit Brussel University of Antwerp
Although the core cerebrospinal fluid Alzheimer's disease (AD) biomarkers amyloid-β (Aβ1-42) and tau show a high diagnostic accuracy, there are still limitations due to overlap in the biomarker levels with other neurodegenerative and dementia disorders. During Aβ1-42 production and clearance in the brain, several other Aβ peptides and amyloid precursor protein fragments are formed that could potentially serve as biomarkers for this ongoing ...
Peptide biomarkers for the diagnosis of dengue infection University of Antwerp Institute of Tropical Medicine
Potential of protein phosphatase inhibitor 1 as biomarker of pancreatic β-cell injury in vitro and in vivo Vrije Universiteit Brussel KU Leuven
There is a need for plasma-based tests that can directly measure the extent of β-cell injury in vivo in patients receiving islet grafts and in animal models. In this study, we propose protein phosphatase 1, regulatory (inhibitor) subunit 1A (PPP1R1A) as a novel biomarker for acute β-cell destruction. Liquid chromatography-tandem mass spectrometry proteome analysis of fluorescence-activated cell sorter-purified β-cells, tissue-comparative ...