Publications
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Punishment, legitimate policies and values: Penal moderation, dignity and human rights Vrije Universiteit Brussel
Twenty years ago, we described how changing prison populations in western countries result from a complex interaction between criminality, external (demography, economy), internal (criminal justice policies) and intermediate factors (public opinion, politics and media). While the outcome of these interactions is contingent, we advocated a reductionist penal policy in order to curb penal inflation. Subsequent macro-sociological analyses and ...
Autophagy dynamics and modulation in a rat model of renal ischemia-reperfusion injury University of Antwerp KU Leuven
Renal ischemia-reperfusion (IR) injury leading to cell death is a major cause of acute kidney injury, contributing to morbidity and mortality. Autophagy counteracts cell death by removing damaged macromolecules and organelles, making it an interesting anchor point for treatment strategies. However, autophagy is also suggested to enhance cell death when the ischemic burden is too strong. To investigate whether the role of autophagy depends on the ...
Punishment, Legitimacy and the Role of the State: Reimagining More Moderate Penal Policies Vrije Universiteit Brussel
Punishment is without doubt one of the most coercive forms of the exercise of state power. This exercise requires legitimation within a democratic constitutional state. 'Legitimacy' is a multidimensional concept though. Bottoms & Tankebe (2012) have further developed Beetham’s thinking through a dialogic approach to legitimacy in criminal justice, distinguishing audience legitimacy from power holder legitimacy. This article applies these ...
EU Policy on Counterterrorism: Evidences and Alternatives to Penal Populism Vrije Universiteit Brussel
The ongoing rise of populism across the European Union (EU) has relaunched a lively debate on its implications for democracy and the rule of law. Conversely, there has been little discussion about penal populism; namely, a legislative strategy meant to restore the weakened authority of the State and capable of affecting crime perception and principles of criminalisation. Yet, to what extent does penal populism affect the EU policy-making ...
Fetal brain maceration score on postmortem magnetic resonance imaging vs. conventional autopsy KU Leuven
BACKGROUND: Postmortem fetal magnetic resonance imaging (MRI) has been on the rise since it was proven to be a good alternative to conventional autopsy. Since the fetal brain is sensitive to postmortem changes, extensive tissue fixation is required for macroscopic and microscopic assessment. Estimation of brain maceration on MRI, before autopsy, may optimize histopathological resources. OBJECTIVE: The aim of the study is to develop an MRI-based ...
Modulation of protein fermentation does not affect fecal water toxicity: a randomized cross-over study in healthy subjects KU Leuven
Protein fermentation results in production of metabolites such as ammonia, amines and indolic, phenolic and sulfur-containing compounds. In vitro studies suggest that these metabolites might be toxic. However, human and animal studies do not consistently support these findings. We modified protein fermentation in healthy subjects to assess the effects on colonic metabolism and parameters of gut health, and to identify metabolites associated with ...