Autophagy at synapses: proteopathic stress and neurodegeneration in Parkinson's disease KU Leuven
Neuronal communication is essential for normal brain function and occurs at specialized contact sites called synapses. It has become increasingly apparent that synaptic dysfunctions contribute to neurological disorders like Parkinson’s disease (PD). Here I investigate the role of Endophilin A (Endo A), a synaptic protein that is involved in synaptic vesicle recycling and synaptic autophagy and which is functionally linked to several PD ...