Projects

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Salivary metabolomics as a new tool for unraveling stress obesity pathways in adolescents from a clinical public health perspective Ghent University

Stefaan De Henauw
Department of Public Health and Primary Care, Department of Veterinary Public Health and Food Safety

The high prevalence and treatment resistance of obesity urges further exploration into early diagnosis and prevention. This is especially important at young age, when metabolic and psychological development are ongoing. Psychological factors like stress can favor obesity, but researchers still struggle with the complex processes towards disease susceptibility. This project aims to elucidate pathways and identify potential clinical biomarkers ...

The public health impact of congenital toxoplasmosis (CT) and cytomegalovirus (cCMV) infection in Belgium Ghent University

Pierre Dorny
Department of Translational Physiology, Infectiology and Public Health

CT and cCMV can lead to lifelong disabilities and fetal or neonatal death. The goal of this project is to assess the public health impact of CT and cCMV in Belgium by using available data sources. This will generate the data needed for breaking the vicious circle of under recognition and neglect

Balancing socio-economic and public health impact of COVID-19 for its sustainable control and mitigation (SOPHIA) KU Leuven

Thomas Neyens
Leuven Biostatistics and Statistical Bioinformatics Centre (L-BioStat)

Given the uncertainty about the further development of the
COVID-19 pandemie, decision makers urgently need to balance the immediate public health impact of
the virus and the - yet uninvestigated - psychological and socio-economic impacts of the mitigation
measures that were imposed to safeguard our health care system. Just as the spread of COVID-19
itself, these effects are spatially heterogeneous and scale dependent, ...

Balancing socio-economic and public health impact of COVID-19 forits sustainable control and mitigation (SOPHIA) Ghent University

Ingmar Nopens
Department of Environment, Department of Psycho-analysis and clinical consulting, Department of Data analysis and mathematical modelling, Department of Economics

Given the uncertainty about the further development of the

COVID-19 pandemic, decision makers urgently need to balance the

immediate public health impact of the virus and the - yet

uninvestigated - psychological and socio-economic impacts of the

mitigation measures that were imposed to safeguard our health care

system. Just as the spread of COVID-19 itself, these effects are

spatially heterogeneous and ...

Combining phylodynamics and agent-based HIV transmission modelling to advance epidemiological methodology and evidencebased public health policies for HIV prevention and treatment Hasselt University

Niel HENS
Centre for Statistics
High rates of HIV transmission remain an important public health challenge. HIV Phylodynamics is the study of HIV viral genetic data to understand the HIV transmission dynamics behind an HIV epidemic. Agent-based HIV transmission models simulate how HIV epidemics evolve, based on estimates and assumptions of infectious disease parameters. Both methodologies could be combined synergistically, but this area of epidemiological methodology is ...

Balancing socio-economic and public health impact of COVID-19 for its sustainable control and mitigation (SOPHIA) Hasselt University

Centre for Statistics
Given the uncertainty about the further development of the COVID-19 pandemic, decision makers urgently need to balance the immediate public health impact of the virus and the - yet uninvestigated - psychological and socio-economic impacts of the mitigation measures that were imposed to safeguard our health care system. Just as the spread of COVID-19 itself, these effects are spatially heterogeneous and scale dependent, hence the need to study ...

Celluloepidemiology: generating and modeling SARS-COV-2 specific T-cell responses on a population level for more accurate interventions in public health. University of Antwerp

Benson Ogunjimi
Laboratory for Experimental Hematology (LEH), Centre for the Evaluation of Vaccination (CEV), ADReM Data Lab (ADReM), Laboratory of Medical Microbiology (LMM), Primary and interdisciplinary care Antwerp (ELIZA), Centre for Health Economics Research and Modelling of Infectious Diseases (CHERMID)
Mathematical simulation models have become indispensable tools for forecasting and studying the effectiveness of intervention strategies such as lockdowns and screening during the SARS-CoV-2 pandemic. Estimation of key modeling quantities uses the serological footprint of an infection on the host. However, although depending on the type of assay, SARS-CoV-2 antibody titers were frequently not found in young and/or asymptomatic individuals and ...

Quantification of varicella-zoster virus boosting mechanisms with their public health implications for vaccination. University of Antwerp

Philippe Beutels
Vaccine & Infectious Disease Institute (VAXINFECTIO)
The general aim is (1) to quantify exogenous boosting by means of an observational longitudinal study, (2) implement this result in newly adapted epidemiological models, (3) assess the population effects of vaccination against VZV and (4) apply this to inform a cost-utility analysis examining vaccination against VZV.

Lifting barriers towards obtaining actionable public health information from pathogen genomes: model advancement, performance evaluation and application to respiratory syncytial virus types A and B KU Leuven

Philippe Lemey
Laboratory of Clinical and Epidemiological Virology (Rega Institute)

Molecular epidemiology approaches can glean epidemiological information from pathogen genomes, and have grown into an important instrument across infectious disease research. Harnessing these methods for actionable information to public health -an important goal in e.g. HIV research- requires the ability to obtain timely and unbiased information on key epidemic processes such as migration. The adoption of model-based phylogenetic inference of ...