Regulation of intercellular communication via extracellular tumor vesicles generated under the influence of elastokines KU Leuven
Pancreatic cancer is currently the fourth leading cause of cancer death in Europe. Pancreatic cancer is a tumor with a very poor prognosis, even if surgery is possible. Pancreatic cancer is characterized by the presence of a transformed microenvironment. This transformed microenvironment involves inflammatory remodelling of the stroma of tissue. This results in accumulation of activated fibroblasts and degradation of the extracellular matrix, ...