Multimodal PET-MRI brain imaging of white matter pathology in late life depression KU Leuven
Depression in later life (late-life depression: LLD) is a common but debilitating psychiatric disorder, which is associated with cerebrovascular disease. Understanding the neurobiological mechanisms underlying LLD is crucial for new solutions for its prevention and treatments. Previous studies have revealed that macrostructural white matter damage is associated with LLD, but little is known about microstructural alterations. The aim of this ...