Mitochondrial diseases: from diagnosis, over pathophysiology, to treatment Ghent University
Diagnostics:
The current diagnostic platform will be expanded with the implementation of transcriptomics and proteomics in collaboration with the CMGG and VIB. We also plan to focus on more organ-specific testing by setting up neuronal iPSCs in which mitochondrial function will, firstly, be evaluated by means of classical biochemical techniques (spectrophotometry, BN-PAGE, oxygen consumption).
Pathophysiology:
The study ...