Projects
Oncotolk. An expolorative study on communication problems in interpreter-mediated consultations with migrant oncology patients. Ghent University
The ultimate goal of this project is to optimize the provision of care for migrant cancer patients and their families who need to rely on interpreters. We will do so by creating the conditions that enable both patients and theis next of kin to better understand the information provided to them in order for them to be able to be involved in the process of shared decision-making. This means that we aim to improve the interaction between ...
Oncotolk. An explorative study on communication problems in interpreter-mediated consultations with migrant oncology patients. University of Antwerp
Evaluation of p53 aggregation as a drug target in oncology Ghent University
This project includes four major research themes: - Incidence: Using immunofluorescence different tumors will be screened to determine the incidence of protein aggregation. In this way, the application potential aggregation of targeted drugs can be evaluated. In addition, there will be a new test for use are developed on an existing diagnostic platform. This test will be evaluated in selected international multicenter studies. -Causaliteit: ...
Future of Personalised Medicine: Quality Assurance of Oncology Biomarker Testing is Essential KU Leuven
Future of personalised medicine: quality assurance of oncology biomarker testing is essentialTumour specific mutations play an increasing role in the selection of targeted therapy. However testing for
these mutations is not straightforward and errors occur. This could lead to a denial of treatment to patients who
would actually benefit from it, or a superfluous use of high-priced therapeutic agents and unnecessary sideeffects in ...
Development of Temporal Separation Methods for Simultaneous Dual Tracer PET Imaging with in vivo Validation for Applications in Oncology and Neurology. University of Antwerp
Validation of Actionable Genomic ABerrations in a paediatric Oncology Network for Doctorate students Ghent University
High-risk neuroblastoma (HR-NB) patients undergo intensive multi-modal treatment, with over half succumbing to their disease. HR-NB cells exhibit replicative stress, and targeting DNA damage response (DDR) pathways represents a viable therapeutic option. Pharmalogical CDK12 inactivation leads to downregulation of DDR genes, selectively reducing viability of NB cells. A novel zebrafish HR-NB xenograft model for high-throughput compound testing ...
Data platform Oncology – Limburg Clinical Research Center (LCRC) Hasselt University
Forwarding precision oncology by integrating cohort-derived molecular and clinical information. Ghent University
Combining molecular data and clinical annotation of tumor cohorts, now available in a public, but increasingly also in a clinical context has the potential to greatly advance clinical practice. However, the integration of these data is non-trivial. Therefore, we will develop methods to analyze such cohort-derived molecular and clinical information and apply them in the context of drug-based precision oncology.