Projects
An optical imaging system for in vivo bioluminescent and fluorescent imaging in small laboratory animals. KU Leuven
Super-resolved imaging of the swarming behavior of nanoparticles during optical trapping: the role of optohydrodynamics KU Leuven
Half of the Nobel Prize in Physics 2018 was awarded to Prof. Arthur Ashkin for his work in the development of optical trapping (also known as optical tweezers) and its biological implications. Optical trapping is the craft of manipulating objects with light and it is based on the phenomena that light scattering introduces an optical force to a (nano/micro)-structure. This optical force can be used to move this particle in 3D, study its ...
Synthesis and characterization of amphiphilic lanthanide chelates as potential contrast agents for bimodal MRI and optical imaging KU Leuven
The powerful in vivo technique of magnetic resonance imaging (MRI) is ubiquitous in clinical diagnostics and optical imaging is becoming an emerging technique of interest. Each imaging technique has its own strengths and weaknesses, the combination of different, complementary techniques can overcome inherent limitations that are associated with one individual technique. Whereas MRI is ideal for whole body images due to its good spatial ...
Super-sensitive fluorescence biochip-based detection by combining freeform optical design and computational imaging Vrije Universiteit Brussel
detection of low-volume, low-concentration biomarkers. Fluorescence
microscopy has been one of the most preferred methods due to its
superiority in detecting specified molecules such as antibodies and
DNA. The development of a disposable, low-cost, super-sensitive
fluorescence-based biochip is crucial for point-of-care clinical
diagnostics. ...
Development and validation of optical imaging tools for advanced preclinical cancer research KU Leuven
The main aim of the current project lies in the development of a novel in vivo preclinical imaging system that allows researchers to study in a non-invasive manner interesting oncology-related parameters as a function of time at an unprecedented sensitivity. To reach this goal, a recently established imaging method called Aka-BLI will be used, in combination with existing probes to enable a rapid and cost-efficient method for high-throughput ...
MULTISCALE - The UHasselt MultiScale Optical Imaging Core: Infrastructure for nano- to centimeter length scale microscopy and analysis of 'big' 4D datasets Hasselt University
Carbon nanomaterial enhanced optical fibres for biomedical imaging and sensing (CHARMING). University of Antwerp
A multimodal non-linear optical platform for 2|3-photon excitation and 2nd|3rd harmonic imaging deep inside living tissues and animals KU Leuven
Unbiased understanding of cellular networks and circuits, is
only possible by studying them in their native and intact
environment. To achieve this, live 3-dimensional (3D)
imaging is required. However, regular microscopy
techniques do not allow deep penetration, and therefore,
tissue dissection remains necessary to optically reach cells
of interest. However, as redshifted infrared (IR) light
scatters less, ...
Carbon nanomaterial enHanced opticAl fibRes for bioMedical Imaging and SeNsinG Vrije Universiteit Brussel
At the same time, new so-called ...