Neuro-hormonal control of hunger, nutrient tolerance and food intake : from nutrient sensing to reward sensitivity. KU Leuven
Intense signalling occurs between the gastrointestinal tract and the brain. Under normal conditions, most of these signals are not perceived. We will test the hypothesis that this “Gut-to-Brain” signalling is in fact crucial for the control of food intake. We propose that the capacity for the stomach to relax during food intake, as well as the activation of anti-nociceptive pathways during meal ingestion are crucial determinants of the volume ...