Uncovering short- and long-term circuit mechanisms of locomotor rehabilitation after spinal cord injury. KU Leuven
Severe spinal injuries disrupt communication between the brain and circuits below the lesion. Therapeutic approaches aim for functional recovery by facilitating axonal growth, removing growth barriers, or replacing lost cells. However, all approaches face a common challenge: the spinal cord below the injury must adapt to function with limited brain input. Rehabilitative training facilitates locomotor recovery by “teaching” the spinal cord to ...