Projects
Multimodal monitoring of electrophysiological signals in childhood epilepsy and neonatal encephalopathy KU Leuven
</>Summary
EEG records electrical activity in the brain generated by pyramidal cells forming large neuronal networks. EEG monitoring provides a constant assessment of brain function and has 3 major applications in neurological practice. It can be used to appreciate epileptic activity in patients with ...
Discovery of Antiseizure Compounds in Zebrafish Models for the Treatment of Drug-Resistant Epilepsy KU Leuven
With 70 million people affected worldwide is epilepsy one of the most common neurological diseases characterized by unpredictable, unprovoked, recurrent seizures. Moreover, the disease is often accompanied by psychiatric and cognitive comorbidities, affecting dramatically the quality of life of patients. So far, pharmacological intervention is the first-line treatment for epilepsy. Unfortunately, about 30% of patients experience seizures that ...
Characterizing the esophageal function of infants in the NICU. KU Leuven
Infants admitted in the neonatal unit commonly present with feeding problems such as decreased oral intake and feeding intolerance. These infants may suffer from complex diseases such as prematurity or congenital malformations. The origin of these feeding problems may be disease-specific or may be secondary to many factors such as severity of the illness, concomitant medication and surgical interventions.
“Healthy” preterm ...
Development of an extended animal model for perinatal drug testing for Bronchopulmonary Dysplasia KU Leuven
Premature birth affects 11% of all pregnancies and is the leading cause of death in neonates worldwide. Advances in perinatal medicine have resulted in the more accurate prediction of preterm birth and more timely interventions leading to increased neonatal survival rates also for extreme preterm babies (≤28 weeks). However, the associated morbidity in survivors remains significant, especially in the pulmonary and central nervous system. At ...