The laboratory for Neurobiology and Gene Therapy is committed to gain insight in the underlying pathology of Parkinson's Disease (PD) and more recently Multiple System Atrophy (MSA), on both the molecular and cellular level. We are specifically focussing on the proteins α-synuclein and LRRK2, two key players in sporadic and familial PD. The underlying idea is that better disease models and insights in the molecular pathogenesis are required ...
Animal Physiology and Neurobiology KU Leuven
The Laboratory of Neurobiology focuses on the mechanisms of acute and chronic axonal and neuronal degeneration and regeneration, aiming to contribute to the development of new therapeutic strategies for neurodegenerative disorders. We intensively study motor neuron diseases (amyotrophic lateral sclerosis (ALS) and hereditary motor neuropathies), frontotemporal dementia (FTD) and stroke.
Major research questions focus on cell type vulnerability and single-cell heterogeneity, protein aggregation and proteopathic stress, synaptic function, as well as microglial activation and neuroimmunology.
Translational Neurobiology University of Antwerp
Laboratory of Stem Cell and Developmental Neurobiology (VIB-KU Leuven Center for Brain & Disease Research) KU Leuven
We want to force a breakthrough in the cure of neuronal and neurodegenerative disorders. This requires a deep understanding of normal brain function and translation of this knowledge into a solid mechanistic understanding of disease mechanisms.
Laboratory of Structural Neurobiology KU Leuven
The Laboratory of Structural Neurobiology is interested in understanding the structural basis of ion channel function. Ion channels are integral membrane proteins that act as molecular switches of electrochemical signaling in the central nervous system. Our specific goal is to understand the structural determinants of ligand recognition, the mechanism of channel gating and ion selection and permeation. Our methodological approach is based on ...
Theoretical neurobiology University of Antwerp
VIB CMN - Neurodegenerative Brain Diseases Group University of Antwerp
Pathologic Biochemistry and Physiology Vrije Universiteit Brussel
The department of Pathologic Biochemistry and Physiology is responsible for (post)graduate teaching in this field. It also plays a co-ordinating role in the organisation of courses and training in medical research. Within its own laboratories, the department offers training to Master and Ph.D. students in research projects in the field of diabetes. The research activities are undertaken within the broader framework of the Diabetes Research ...