The effect of the microbiome on nasal epithelial barrier function in chronic rhinosinusitis KU Leuven
Chronic rhinosinusitis (CRS) is characterized by mucosal inflammation in the nasal cavity and the paranasal sinuses and effects approximately 11% of the European population. CRS is generally devided into two phenotypes depending on the presence or absence of nasal polyps, namely CRS with nasal polyps (CRSwNP) and CRS without nasal polyps (CRSsNP). Despite the available treatment strategies, up to 40% of CRS patients remain uncontrolled even ...