Single-molecule Protein Dynamics using Correlative Nanopore and Fluorescence Measurements KU Leuven
Proteins are the primary functional elements in living organisms. Their function is subject to their structure and dictated by the structural changes they undergo during their functional cycle, with protein dynamics being a key component of chemical catalysis, regulation, and molecular recognition. Generally, these are challenging to fully observe at the ensemble level due to ensemble averaging.
Single-molecule protein dynamics are ...