Projects

The SARS‐CoV‐2 pandemic has exposed how unprepared our society was in preventing the propagation of highly infectious diseases, protecting the healthcare providers and patients, and efficiently organizing the logistics, while managing large numbers of patients. For the past two years, hospitals have battled to mitigate the spread of the virus in their facilities, a challenge that included the need to daily dispose of ...

Recently, a new approach based on non-thermal plasma (NTP) to treat cancer cells is gaining interest in the medical field. Plasma is an ionized gas. It is a highly reactive mixture, containing electrons, ions, radicals and energetic neutrals, while still operating at room temperature. Precisely this combination of reactive species and low gas temperature makes it suitable for treating biological samples. It is suggested that the killing capacity ...

In the context of clinical treatment of cancers, a major challenge involves the precise delivery of therapeutic agents to the tumor while limiting off-target effects. This is true for multiple treatment modalities including radiotherapy and non-thermal plasma (NTP) therapy. Hence, the main focus of this research project is to introduce the design of a supervisory control structure into a patient-in-the-loop therapeutic application. This system ...

Cancer immunotherapy strategies leave room for improvement. Given that a 'one-size-fits-all' approach is not the solution due to tumor heterogeneity, personalized therapy is the way forward. It is my mission to overcome hard-to-treat solid tumors and to push boundaries in achieving effective personalized immunotherapies. To accomplish this, the immunosuppressive nature of the tumor microenvironment needs to be overcome, allowing to significantly ...