Synthese van suikergemodificeerde a-galactosylveramide-analogen als Th1- polariserende NKT-vel antigenen. Ghent University
Synthesis of sugar- modified alpha-galactosylceramide (KRN 7000) analogues that potentially induce a Th1- polarised cytokine response mediated by NKT cells. The proposed modifications intent to establish an improved binding affinity with the CD1d protein, which should result in a bias towards a TH1 respons.