1,25(OH)2D3 in thyroid tumorigenesis and development KU Leuven
This doctoral research project aimed to gain insight into the role of 1,25(OH)2D3, the active form of vitamin D, in the normal thyroid and in the pathogenesis, progression and treatment of thyroid cancer. As treatment modalities are very limited in case of poorly differentiated or anaplastic thyroid cancer, resulting in a very poor survival, the effect of treatment with 1,25(OH)2D3 in anaplastic thyroid cancer was investigated using different ...