Study of intercellular transmission and neurotoxicity of alfa-synuclein in an animal model for Parkinson's disease using optogenetic neuromodulation KU Leuven
Parkinson’s disease, dementia with Lewy Bodies and multiple system atrophy are age-related and devastating neurodegenerative disorders that are characterized by the presence of large proteinaceous clumps of the ɑ-synuclein protein scattered throughout the patient’s central nervous system. The identification of ɑ-synuclein in Lewy bodies made it clear that this protein has a central role in the etiopathogenesis of several age-related ...