Publications
Mycobacterium tuberculosis strains of Beijing genotype are rarely observed in tuberculosis patients in South America Institute of Tropical Medicine
Evolution of Mycobacterium tuberculosis complex lineages and their role in an emerging threat of multidrug resistant tuberculosis in Bamako, Mali Institute of Tropical Medicine
In recent years Bamako has been faced with an emerging threat from multidrug resistant TB (MDR-TB). Whole genome sequence analysis was performed on a subset of 76 isolates from a total of 208 isolates recovered from tuberculosis patients in Bamako, Mali between 2006 and 2012. Among the 76 patients, 61(80.3%) new cases and 15(19.7%) retreatment cases, 12 (16%) were infected by MDR-TB. The dominant lineage was the Euro-American lineage, Lineage ...
Evaluation of thin-layer agar 7H11 for the isolation of Mycobacterium tuberculosis complex Institute of Tropical Medicine
Further studies on African strains of Mycobacterium tuberculosis. Comparison with M. bovis and M. microti Institute of Tropical Medicine
Rapid detection of multidrug-resistant Mycobacterium tuberculosis in Cotonou (Benin) using two low-cost colorimetric methods: resazurin and nitrate reductase assays Institute of Tropical Medicine University of Antwerp Ghent University
Low levels of second-line drug resistance among multidrug-resistant Mycobacterium tuberculosis isolates from Rwanda Institute of Tropical Medicine University of Antwerp
Exploring acyclic nucleoside analogues as inhibitors of Mycobacterium tuberculosis thymidylate kinase Institute of Tropical Medicine University of Antwerp
Resazurin microtiter assay plate: simple and inexpensive method for detection of drug resistance in Mycobacterium tuberculosis Institute of Tropical Medicine
Standardization of a TaqMan-based real-time PCR for the detection of Mycobacterium tuberculosis-complex in human sputum Institute of Tropical Medicine University of Antwerp
Real-time polymerase chain reaction (qPCR) was optimized for detecting Mycobacterium tuberculosis in sputum. Sputum was collected from patients (N = 112) with suspected pulmonary tuberculosis, tested by smear microscopy, decontaminated, and split into equal aliquots that were cultured in Löwenstein-Jensen medium and tested by qPCR for the small mobile genetic element IS6110. The human ERV3 sequence was used as an internal control. 3 of 112 ...