Exercise-induce hyperalgesia, complement system and elastase activation in myalgic encephalomyelitis/chronic fatigue syndrome : a secondary analysis of experimental comparative studies Ghent University KU Leuven Vrije Universiteit Brussel University of Antwerp
Background and aims: The interaction between the immune system and pain has been thoroughly explored in the recent decades. The release of inflammatory mediators from immune cells has the capability of activating neurons and glial cells, in turn sensitizing the nervous system. Both immune system alterations and pain modulation dysfunctions have been shown in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) following exercise. However, ...