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Global prevalence, cascade of care, and prophylaxis coverage of hepatitis B in 2022: a modelling study KU Leuven University of Antwerp
Estimation of Campylobacter prevalence and culture methods sensitivity in adsence of a gold-standard detection method: a statistical modelling helper Ghent University
Global change in hepatitis C virus prevalence and cascade of care between 2015 and 2020: a modelling study KU Leuven Hasselt University University of Antwerp
BACKGROUND: Since the release of the first global hepatitis elimination targets in 2016, and until the COVID-19 pandemic started in early 2020, many countries and territories were making progress toward hepatitis C virus (HCV) elimination. This study aims to evaluate HCV burden in 2020, and forecast HCV burden by 2030 given current trends. METHODS: This analysis includes a literature review, Delphi process, and mathematical modelling to estimate ...
Global prevalence and genotype distribution of hepatitis C virus infection in 2015 : a modelling study Ghent University University of Antwerp KU Leuven
Background The 69th World Health Assembly approved the Global Health Sector Strategy to eliminate hepatitis C virus (HCV) infection by 2030, which can become a reality with the recent launch of direct acting antiviral therapies. Reliable disease burden estimates are required for national strategies. This analysis estimates the global prevalence of viraemic HCV at the end of 2015, an update of-and expansion on-the 2014 analysis, which reported 80 ...
Hepatitis C virus prevalence and level of intervention required to achieve the WHO targets for elimination in the European Union by 2030: a modelling study Hasselt University KU Leuven University of Antwerp
Background Hepatitis C virus (HCV) is a leading cause of liver-related morbidity and mortality worldwide. In the European Union (EU), treatment and cure of HCV with direct-acting antiviral therapies began in 2014. WHO targets are to achieve a 65% reduction in liver-related deaths, a 90% reduction of new viral hepatitis infections, and 90% of patients with viral hepatitis infections being diagnosed by 2030. This study assessed the prevalence of ...
Joint Modeling of HCV and HIV Infections among Injecting Drug Users in Italy Using Repeated Cross-Sectional Prevalence Data Hasselt University University of Antwerp
During their injecting career, injecting drug users (IDUs) are exposed to some infections, like hepatitis C virus (HCV) infection and human immunodeficiency virus (HIV) infection, due to their injecting behavioral risk factors, such as sharing syringes or other paraphernalia containing infected blood, or sexual behavior risk factors. If we consider that these IDUs might belong to a social network of people where these behavioral risk factors are ...
Estimating incidence and prevalence rates of chronic diseases using disease modeling KU Leuven
BACKGROUND: Morbidity estimates between different GP registration networks show large, unexplained variations. This research explores the potential of modeling differences between networks in distinguishing new (incident) cases from existing (prevalent) cases in obtaining more reliable estimates. METHODS: Data from five Dutch GP registration networks and data on four chronic diseases (chronic obstructive pulmonary disease [COPD], diabetes, heart ...
An updated meta-analysis of the distribution and prevalence of Borrelia burgdorferi s.l. in ticks in Europe Institute of Tropical Medicine
Background: The bacteria of the group Borrelia burgdorferi s.l. are the etiological agents of Lyme borreliosis in humans, transmitted by bites of ticks. Improvement of control measures requires a solid framework of the environmental traits driving its prevalence in ticks.
Methods: We updated a previous meta-analysis of the reported prevalence of Borrelia burgdorferi s.l. in questing nymphs of Ixodes ricinus with a literature search ...