Development and streamlining a validation and implementation workflow for model-informed precision dosing for biologicals and antimicrobials KU Leuven
Drug Delivery and Disposition, Clinical Pharmacology and Pharmacotherapy, Therapeutic and Diagnostic Antibodies, Translational Research in GastroIntestinal Disorders, Laboratory for Clinical Infectious and Inflammatory Disorders
It has been shown that in many specific patient populations, a standard dosing approach is not always warranting efficacy and safety. Some patients benefit from an adapted and personalized dosing strategy, in which pharmacokinetic target attainment is correlating with pharmacodynamics. Many pharmacokinetic studies, conducted in the field of antimicrobial therapy and anti-inflammatory biologicals, of us and others allowed to model exposure and PK ...