Publications

1 - 7 of 7 results

Sorteren op
Search term:

Cardiac contractility modulation improves long-term survival and hospitalizations in heart failure with reduced ejection fraction. KU Leuven

Daniel Burkhoff
AIMS: Cardiac contractility modulation (CCM) improves symptoms and exercise tolerance and reduces heart failure (HF) hospitalizations over 6-month follow-up in patients with New York Heart Association (NYHA) class III or IV symptoms, QRS < 130 ms and 25% ≤ left ventricular ejection fraction (LVEF) ≤ 45% (FIX-HF-5C study). The current prospective registry study (CCM-REG) aimed to assess the longer-term impact of CCM on hospitalizations and ...

Cardiac contractility modulation treatment in patients with symptomatic heart failure despite optimal medical therapy and cardiac resynchronization therapy (CRT) KU Leuven

Juergen Kuschyk, Herbert Naegele, Karl Heinz-Kuck, Christian Butter, Thomas Lawo, Dietmar Wietholt, Susanne Roeger, David Gutterman, Daniel Burkhoff, Benny Rousso, et al.
BACKGROUND: A significant proportion of patients receiving CRT are non-responders. We evaluated the efficacy of Cardiac Contractility Modulation in subjects with reduced LVEF who, despite cardiac resynchronization therapy (CRT), continued to experience clinically significant symptoms. METHODS: This was a multi-center, open label, treatment-only, feasibility study of 17 CRT non-responders who received CCM therapy. Changes in NYHA class, ejection ...

Catheter Ablation versus Medical Therapy of Atrial Fibrillation in Patients with Heart Failure: An Updated Systematic Review and Meta-Analysis of Randomized Controlled Trials Vrije Universiteit Brussel

Michele Magnocavallo, Antonio Parlavecchio, Giampolo Vetta, Carola Gianni, Marco Polselli, Francesco De Vuono, Luigi Pannone, Sanghamitra Mohanty, Filippo Maria Cauti, Rodolfo Caminiti, et al.
Background: Atrial fibrillation (AF) and heart failure (HF) often coexist and synergistically contribute to an increased risk of hospitalization, stroke, and mortality. Objective: To compare the efficacy of catheter ablation (CA) versus medical therapy (MT) in HF patients with AF. Methods: Electronic databases were queried for randomized controlled trials (RCTs) of CA versus MT of AF in patients with HF. Risk ratios (RRs), mean differences ...

Catheter Ablation versus Medical Therapy of Atrial Fibrillation in Patients with Heart Failure: An Updated Systematic Review and Meta-Analysis of Randomized Controlled Trials Vrije Universiteit Brussel

Michele Magnocavallo, Antonio Parlavecchio, Giampolo Vetta, Carola Gianni, Marco Polselli, Francesco De Vuono, Luigi Pannone, Sanghamitra Mohanty, Filippo Maria Cauti, Rodolfo Caminiti, et al.
Background: Atrial fibrillation (AF) and heart failure (HF) often coexist and synergistically contribute to an increased risk of hospitalization, stroke, and mortality. Objective: To compare the efficacy of catheter ablation (CA) versus medical therapy (MT) in HF patients with AF. Methods: Electronic databases were queried for randomized controlled trials (RCTs) of CA versus MT of AF in patients with HF. Risk ratios (RRs), mean differences ...

Comparative effects of high intensity interval training versus moderate intensity continuous training on quality of life in patients with heart failure: Study protocol for a randomized controlled trial KU Leuven

Véronique Cornelissen
© 2015 The Authors. Published by Elsevier B.V. Purpose To compare the effect of high intensity interval training (HIIT) and moderate intensity continuous training (MICT) on physical fitness and quality of life (QoL) in patients with chronic heart failure (CHF). Methods Twenty-two male CHF patients (LVEF < 45%, mean age 53.8 ± 8 yr) were studied before and after 12 weeks of supervised aerobic training for 60 min, three times a week. Patients ...

Effects of the long-term administration of nebivolol on the clinical symptoms, exercise capacity, and left ventricular function of patients with diastolic dysfunction: results of the ELANDD study University of Antwerp

Marco Metra, Otto Kamp, Gilles De Keulenaer, Burkert Pieske, Jose Zamorano, Panos E. Vardas, Michael Boehm, Livio Dei Cas
Aims We hypothesized that nebivolol, a beta-blocker with nitric oxide-releasing properties, could favourably affect exercise capacity in patients with heart failure and preserved left ventricular ejection fraction (HFPEF). Methods and results A total of 116 subjects with HFPEF, in New York Heart Association (NYHA) functional class II-III, with left ventricular ejection fraction (LVEF) >45%, and with echo-Doppler signs of LV diastolic ...

Intravenous immunoglobulin therapy in adult patients with idiopathic chronic cardiomyopathy and cardiac parvovirus B19 persistence: a prospective, double-blind, randomized, placebo-controlled clinical trial KU Leuven

Stephane Heymans
AIMS: Previous uncontrolled studies suggested a possible benefit of intravenous immunoglobulin (IVIg) in parvovirus B19 (B19V)-related dilated cardiomyopathy (DCM). This randomized, double-blind, placebo-controlled, single-centre trial investigated the benefits of IVIg beyond conventional therapy in idiopathic chronic DCM patients with B19V persistence. METHODS AND RESULTS: Fifty patients (39 men; mean age 54 ± 11 years) with idiopathic chronic ...