Projects
Synaptic density, tau and multiparametric PET-MR for quantitative functional assessment and prognosis in stroke and mild cognitive impairment KU Leuven
There are no reliable biomarkers to predict recovery, assess prognosis or objectively monitor interventions in stroke and amnestic mild cognitive impairment (aMCI) due to Alzheimer’s disease. Two major, related pathological hallmarks common to these disorders are a decrease in synaptic connectivity, which may involve various neurotransmitters, and an accumulation of tau protein deposits. These are associated with disturbances in white matter ...
Synaptic density, tau and multiparametric PET-MR for quantitative functional assessment and prognosis in mild cognitive and behavioural impairment KU Leuven
With annually 9.9 million new cases worldwide and as one of the
costliest diseases, the impact of dementia cannot be underestimated.
Although research in this domain has made significant progress,
major challenges still lie ahead. There is a growing need of
biomarkers with the capacity to diagnose Alzheimer’s disease (AD) in
an early stage, predict prognosis for prodromal patients and monitor
...Characterisation and validation of biological markers of dementia and mild cognitive impairment. University of Antwerp
Cognitive decline in Alzheimer's disease: motoric, cognitive and linguistic aspects of sentence production. University of Antwerp
Cognitive decline in Alzheimer's disease: motoric, cognitive and linguistic aspects of sentence production University of Antwerp
Effect of hearing loss and vestibular decline on cognitive function in older subjects: correlation with cortical auditory evoked potentials and mri brain volume changes. University of Antwerp
Molecular genetic analysis of Alzheimer dementia. University of Antwerp
Sentence construction in health and neurological disease: an individualized approach using magnetoencephalography and contextualized models of meaning KU Leuven
Language is capable of conveying a seemingly unlimited amount of ideas. The possibility to flexibly combine words into sentences underlies this power. Using recent advances in linguistics & neuroimaging, our goal is to elucidate the neural computations underpinning sentence construction in healthy controls and patients with aphasia.The brain can extract the meaning of a single word in 400 milliseconds. Which neural computations are ...