Publications
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Extracellular microRNAs exhibit sequence-dependent stability and cellular release kinetics Ghent University
Random walks on mutual microRNA-target gene interaction network improve the prediction of disease-associated microRNAs Ghent University
A review of sample preparation for purification of microRNAs and analysis by mass spectrometry methods Ghent University
Spotlight on microRNAs in allergy and asthma Ghent University
Deep sequencing of small RNA libraries reveals dynamic expression patterns of microRNAs in multiple developmental stages of Bactrocera dorsalis Ghent University
MicroRNAs in ovarian cancer: Current status and future perspectives KU Leuven
Epithelial ovarian cancer is the most common cause of death from gynecological malignancies in the Western world. The overall 5-year survival is only 30% due to late diagnosis and development of resistance to chemotherapy. There is, therefore, a strong need for prognostic and predictive markers to help optimize and personalize treatment hence improving the prognosis of ovarian cancer patients. Since 2006, an increasing number of studies have ...
Addressing the role of microRNAs in reprogramming leaf growth during drought stress in Brachypodium distachyon Ghent University
Gene function analysis by artificial MicroRNAs in Physcomitrella patens Ghent University
MicroRNAs (miRNAs) are ~21nt long small RNAs transcribed from endogenous MIR genes which form precursor RNAs with a characteristic hairpin structure. MiRNAs control the expression of cognate target genes by binding to reverse complementary sequences resulting in cleavage or translational inhibition of the target RNA. Artificial miRNAs (amiRNAs) can be generated by exchanging the miRNA/miRNA* sequence of endogenous MIR precursor genes, while ...