Tumor heterogeneity in relapsed or metastatic breast, ovarian and colorectal cancer KU Leuven
Cancer is a genetic disease. Genetic changes or mutations that alter the function of genes, can provide a cell with a selective growth advantage compared to its surrounding cells. Next-generation sequencing is revolutionizing the characterization of these (epi)genetic alterations and is gaining influence on therapy choice and prediction of prognosis. This manuscript describes the results and interpretations derived of genetic ...