Skeletal cell metabolism and bone regeneration KU Leuven
Bone tissue engineering consisting of stem or progenitor cells and growth factors, seeded onto a biocompatible scaffold, is a promising strategy for the healing of large bone defects. However, one of the key challenges in regenerative medicine is the poor survival of the grafted cells, which impedes translation of this strategy to clinical practice. A likely explanation is the lack of vascularization at the transplantation site, resulting in ...