Projects
Effect of metabolic gas transport on the central metabolism of pear fruit (Pyrus communis L.): a computational biologoy approach. KU Leuven
After harvest, apple (Malus x domestica Borkh.) fruit remains metabolically active and continues to ripen. The main goal of postharvest storage is to slow down this metabolic activity and its associated fruit ripening. Therefore, large volumes of apple fruit are routinely stored under controlled atmosphere (CA) conditions (low temperature, low oxygen and high carbon dioxide partial pressures) with recent developments moving ...
MiniBioreactors in support of a generic metabolic platform Ghent University
Although biotech and Meditech seem sometimes two different worlds, many techniques in the INDUSTRIAL applied le biotechnology can also be perfectly used in medical research. E & eacute; n these techniques with a generic application field is “ metabolic flux analysis (MFA) &rdquo ;. With the aid of MFA can the speeds of the reactions of the metabolic network shall be calculated, so that the relative importance of each pathway can be ...
Shifting rainfall regimes: a multi-scale analysis of ecosystem response (REGIME SHIFT). University of Antwerp
Dynamics in the Central Plant Cell Metabolism KU Leuven
The neurovascular link: an unexpectedly important role of metabolism. KU Leuven
A non-metabolic role for glutamine synthetase in regulating endothelial actin cytoskeleton dynamics during vessel sprouting? KU Leuven
Vascular endothelial cells (ECs) pervasively line the lumen of all blood vessels in the body. ECs are quiescent under physiological homeostasis but adopt one of three states in disease. EC activation includes the induction of cell adhesion molecules involved in immune cell recruitment and is associated with inflammatory diseases. EC dysfunction constitutes a state where ECs are no longer able to perform their homeostatic ...
Bioprocess Modelling and Control by Constraint-based Optimization Methods KU Leuven
A recent trend for bioprocess modelling consist of using more complex models to better capture the metabolic behavior of micro-organisms.
In this work, dynamic enzyme-cost flux balance analysis (deFBA), a resource allocation model, is used as framework to describe biotechnological processes.
In addition to making a distinction for multiple biomass components, this method explicitly accounts for a limited enzyme capacity.
The ...
Unraveling the natural isotopic fractionation of Fe accompanying different homeostatic processes for understanding the effect of impaired Fe regulation on its isotopic composition in biological fluids. Ghent University
Understanding the source bio-mechanisms of Fe isotopic fractionation in the human body is crucial knowledge for developing diagnostic tools of one's Fe status. Now, quantification of serum ferritin levels is relied on, but results may be often misleading as they can be affected by inflammation, infection and liver disorders. Isotopic analysis of blood/serum Fe is gaining potential as a robust and reliable indicator of the Fe status. However, ...