Projects
The metabolic syndrome, oxidative stress, and atherosclerosis. KU Leuven
ApoE/transglutaminase 2 deficient mice: a novel animal model that combines features of the metabolic syndrome and atherosclerotic plaque destabilization? University of Antwerp
Molecular background and practical therapeutic implications of postconditioning myocardial tissue in a mice model of diabetes and the metabolic syndrome. KU Leuven
As the prevalence of the MS rises rapidly and the components of the MS increase the overall cardiovascular risk synergistically, interest for this syndrome is growing rapidly. The MS leads to very specific cardiomyocyte changes, and as the natural course of the MS is detrimental, it necessitates a tailored approach with correction of the individual risk factors and prevention of the hypertrophic and inflammatory stimuli.
Although IPreC ...
Metabolic syndrome in bipolar disorder: relationships with physical activity, physical fitness and functional exercise capacity. KU Leuven
Individuals with mood disorders have a high risk for cardiovascular diseases. The lack of physical activity and a limited physical fitness are known to be important risk factors for cardiovascular diseases. Individuals with mood disorders should therefore especially be motivated to adopt an active lifestyle. In order to offer clear guidelines, there is first need for reliable assessment. In this research project we want to evaluate the ...
Exercise training in patients with the metabolic syndrome: effect of different training modalities; phenotypical and genotypical determinants of the training response. KU Leuven
Tryptophan metabolism and its impact on host-microbe crosstalk in irritable bowel syndrome Ghent University
Irritable bowel syndrome (IBS) is a widespread disorder for which no cure exists. Tryptophan may be an interesting amino acid to alleviate IBS symptoms, although a large inter-individual variability exists. This is caused by the limited knowledge on the complex host-microbe interactions involved in IBS and in tryptophan metabolism from both human and microbial side. In this project we aim to unravel the key factors for successful tryptophan ...