Exploring the potential of personalized metabolic profiling to evaluate and boost antibiotic activity Ghent University
There is a major discrepancy between the efficacy of antibiotics in vitro and in patients with cystic fibrosis (CF). Hereby, available diagnostic assays to determine bacterial antibiotic susceptibility are often not predictive. The resulting inability to treat lung infections is a major driver of tissue deterioration and contributes to the development of antibiotic resistance. Hence, there is a need to design novel, predictive diagnostics to ...