Publications
Intensity of malaria transmission and the spread of Plasmodium falciparum-resistant malaria: a review of epidemiologic field evidence Institute of Tropical Medicine
Plasmodium malariae after successful treatment of P. falciparum malaria with artemether-lumefantrine Ghent University Institute of Tropical Medicine
Village malaria worker performance key to the elimination of artemisinin-resistant malaria: a Western Cambodia health system assessment Institute of Tropical Medicine
Maplaria: a user friendly web-application for spatio-temporal malaria prevalence mapping Institute of Tropical Medicine
BACKGROUND: Model-based geostatistical (MBG) methods have been extensively used to map malaria risk using community survey data in low-resource settings where disease registries are incomplete or non-existent. However, the wider adoption of MBG methods by national control programmes to inform health policy decisions is hindered by the lack of advanced statistical expertise and suitable computational equipment. Here, Maplaria, an interactive, ...
Geostatistical analysis of Malawi's changing malaria transmission from 2010 to 2017 Institute of Tropical Medicine
Background: The prevalence of malaria infection in time and space provides important information on the likely sub-national epidemiology of malaria burdens and how this has changed following intervention. Model-based geostatitics (MBG) allow national malaria control programmes to leverage multiple data sources to provide predictions of malaria prevalance by district over time. These methods are used to explore the possible changes in malaria ...
Respiratory virus-associated severe acute respiratory illness and viral clustering in Malawian children in a setting with a high prevalence of HIV infection, malaria, and malnutrition Institute of Tropical Medicine
BACKGROUND:  We used data from 4 years of pediatric severe acute respiratory illness (SARI) sentinel surveillance in Blantyre, Malawi, to identify factors associated with clinical severity and coviral clustering.
METHODS:  From January 2011 to December 2014, 2363 children aged 3 months to 14 years presenting to the hospital with SARI were enrolled. Nasopharyngeal aspirates were tested for influenza virus and other respiratory viruses. ...
Mangrove horseshoe crab (Carcinoscorpius rotundicauda Latreille, 1802) populations reveal genetic break in Strait of Malacca, with connectivity along southern coasts of Peninsular Malaysia Vrije Universiteit Brussel
The mangrove horseshoe crab, Carcinoscorpius rotundicauda, has divergent populations between the east and west coasts of Peninsular Malaysia, with the southern coast acting as a land barrier. The actual position of such a genetic break along Peninsular Malaysia as well as the connectivity status of the southernmost C. rotundicauda populations with east and west coast populations remain unexplored, however. The aim was to investigate the ...
Understanding malaria persistence: a mixed-methods study on the effectiveness of malaria elimination strategies in South-Central Vietnam Institute of Tropical Medicine
Despite the scale-up of vector control, diagnosis and treatment, and health information campaigns, malaria persists in the forested areas of South-Central Vietnam, home to ethnic minority populations. A mixed-methods study using an exploratory sequential design was conducted in 10 Ra-glai villages in Bac Ai district of Ninh Thuan province to examine which social factors limited the effectiveness of the national malaria elimination strategy in ...
Reactive, self-administered malaria treatment against asymptomatic malaria infection: results of a cluster randomized controlled trial in The Gambia Institute of Tropical Medicine
BACKGROUND: Selectively targeting and treating malaria-infected individuals may further decrease parasite carriage in low-burden settings. Using a trans-disciplinary approach, a reactive treatment strategy to reduce Plasmodium falciparum prevalence in participating communities was co-developed and tested.
METHODS: This is a 2-arm, open-label, cluster-randomized trial involving villages in Central Gambia during the 2017 and 2018 ...