Publications
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Comparison of the passive mast cell activation test with the basophil activation test for diagnosis of perioperative rocuronium hypersensitivity University of Antwerp
Background Rocuronium is a major cause of perioperative hypersensitivity (POH). Skin tests (STs) and quantification of specific immunoglobulin E antibodies (sIgEs) can yield incongruent results. In such difficult cases, the basophil activation test (BAT) can be helpful. Here, we evaluated the passive mast cell activation test (pMAT) as a substitute of BAT as part of the diagnostic tests for rocuronium allergy. Methods Sera from patients with a ...
Viral load monitoring for people living with HIV in the era of test and treat : progress made and challenges ahead : a systematic review Ghent University
Background: In 2016, we conducted a systematic review to assess the feasibility of treatment monitoring for people living with HIV (PLHIV) receiving antiretroviral therapy (ART) in low and middle-income countries (LMICs), in line with the 90-90-90 treatment target. By 2020, global estimates suggest the 90-90-90 target, particularly the last 90, remains unattainable in many LMICs. This study aims to review the progress and identify needs for ...
Mast cell activation test University of Antwerp
Background Insights into the IgE cross-sensitization and possible cross-reactivity patterns of sera reactive to chlorhexidine (CHX) are still incomplete and are likely to benefit from a functional exploration using a passive mast cell activation test (pMAT). Therefore, we want to study whether the pMAT with CHX-specific IgE (sIgE) enables to depict effector cell degranulation in response to alexidine (ALX), octenidine (OCT) and/or ...
Structural Behavior of Floor Systems Made by Floor Plates—Mechanical Model Based on Test R KU Leuven
In daily engineering practice, the execution of concrete slabs by the mean of precast floor plates is seen as a common and reliable way to create massive slabs. In the last few decades, however, there has been an evolution to flat slabs and other uses where important bending moments must be transferred over the joints between the floor plates. For this kind of application, there is a lack of knowledge and experimental evidence based on ...
The passively sensitized mast cell activation test is a reliable diagnostic for chlorhexidine allergy University of Antwerp
Mast cell activation test in chlorhexidine allergy University of Antwerp
Background Immediate drug hypersensitivity reactions are an increasing public health issue and a frequent cause of life-threatening anaphylaxis. Conventional confirmatory testing include skin tests and, for a few drugs, quantification of drug-specific immunoglobulin E (IgE) antibodies. However, none of these tests are absolutely predictive for the clinical outcome, and can yield false-negative and false-positive results. We performed a ...
Doubly Modified Carlsberg Test combined with Dynamic Light Scattering allows prediction of the primary gushing potential of harvested barley and malt KU Leuven
Despite intensive research on the gushing of carbonated beverages during the last decades, there is no universal method to predict its occurrence and consequently how to avoid the economic losses it induces. Primary gushing can be visualized as the strong overfoaming and/or strong liquid expulsion of liquid when a bottle of carbonated beverage is opened. This process results from the interaction between gaseous CO 2 and class II hydrophobins. ...