Projects
Model based virtual acoustic sensing for augmented system monitoring of flexible multibody systems KU Leuven
The sustainable development and maintenance of vehicles and machines plays an increasingly important role. This involves the challenging task of monitoring and balancing the often conflicting criteria related to human health, profitability and environment. The knowledge of the forces, torques and stresses in components is of great importance to make sure that machines and vehicles stay within safety limits and retain their reliability over ...
Model Based System Engineering approaches for the identification and monitoring of mechatronic systems KU Leuven
This dissertation focuses on the efficient and accurate generation of sensitivity information for various optimization problems characterized by a large design space in the field of flexible multibody system dynamics. These various optimization problems, such as parameter identification, optimal input and topology optimization, enable the mechatronic industry to reach targets on energy-efficiency, performance, reliability, etc. Accurate ...
Model Predictive Control and Innovative System Integration of GEOTABS;-) in Hybrid Low Grade Thermal Energy Systems - Hybrid MPC GEOTABS KU Leuven
The MPC-: GT project brought together a transdisciplinary team of SMEs, large industry and research institutes, experienced in research and application of design and control systems in the combined building and energy world. Based on prior research, supported by (joint) EU and national projects, and practical experience the bottlenecks where identified that prevent at this moment a real breakthrough of geothermal heat pumps (GEO-HP) combined ...
Model Predictive Control and Innovative System Integration of GEOTABS in Hybrid Low Grade Thermal Energy Systems - Hybrid MPC GEOTABS Ghent University
The MPC-GT project brought thogether a transdisciplinary team of SMEs, large industry and research institutes, experienced in research and application of design and control systems in the combined building and energy world. Based on prior research, supported by (joint) EU and national projects, and practical experience the bottlenecks where identified that prevent at this moment a real breakthrough of geothermal heat pumps (GEO-HP) combined ...
Characterization of alpha-synuclein strains from patients with multiple system atrophy in novel model systems. KU Leuven
Misfolded protein aggregates are a common feature of several neurodegenerative diseases. Alfa-synnuclein aggregates with different structural characteristics of strains induce strain-specific pathology resembling pathological hallmarkrs found in PD and MSA patients. In this project we will test aSYN strains derived form the brain of patients with MSA in new cellular and rodent models. This should lead to a better understanding of the ...
Model based design and optimization of anaerobic digestion systems by inon of microbial community dynamics in advanced mathematical models KU Leuven
The project specifically focuses on the effect of changes in substrate composition:
- knowledge on the community response to specific substrate components offers the possibility to engineer the community composition through altering substrate composition
- inclusion of microbial diversity in mathematical models will increase their accuracy, and opens the opportunities for improved simulation, control and optimization of ...
Towards the development of norovirus antiviral drugs: building a unique toolbox of model systems to study the efficacy and mode of action of new inhibitors KU Leuven
Human noroviruses (HuNoVs) are single stranded, positive sense RNA viruses belonging to the Caliciviridae family. HuNoV infections result in vomiting and watery non-bloody diarrhea. Infections occur worldwide and are an important health issue that affects all age groups, resulting annually in 200,000 deaths. Infections occur via the fecal-oral route, by consumption of contaminated food or water and by person-to-person contact. HuNoV ...
Drug delivery systems and in vivo efficacy of the serine protease inhibitor UAMC-00050 in a preclinical model for irritable bowel syndrome. University of Antwerp
Nonlinear and Parametric Model Order Reduction for Second Order Dynamical Systems by the Dominant Pole Algorithm KU Leuven
aerospace products.
In order to gain competitive advantage, manufacturers are continually striving to reduce noise and
vibrations levels.
The numerical analysis of the acousticbehaviour results in huge mathematical models, in particular,
for higher frequency analyses.
This leads to high requirements regarding ...