Combined Highly Active Anti-Retroviral Microbicides Institute of Tropical Medicine
1. To investigate the potential of protease and proteasome inhibitors as microbicides.
2. To develop new small molecule inhibitors of HIV-1 reverse transcriptase and integrase.
3. To develop new small molecule inhibitors of HIV-1 fusion and further the development of novel protein and peptide based inhibitors as microbicides.
4. To test efficacy and safety of novel microbicide combinations using in vitro systems. ...