Projects
ESTEEM 2 - Enabling science and technology through European electron microscopy. University of Antwerp
Enabling 3D scanning probe microscopy for nanoelectronics device analysis and TCAD calibration of advanced technology nodes KU Leuven
Important breakthroughs in nanoelectronics device manufacturing are directly linked to disruptive innovations in the materials characterization domain. Scanning probe microscopy (SPM) is one of these enabling techniques because it can measure a broad range of physical properties (e.g. topography, electrical, and magnetic signals) with unrivaled spatial resolution. Scientific research has been the critical enabler for establishing these ...
Characterization of short- and long-distance neuronal circuits in the enteric nervous system and their specific defects in Hirschsprung’s disease using advanced microscopy and stem cell technology KU Leuven
A distinguishing feature of the gastrointestinal (GI) system is the presence of the enteric nervous system (ENS), a mesh-like network of neurons and glia. The ENS mainly controls GI motility, secretion and local blood flow. During development, vagal neural crest cells enter and migrate down the gut to colonize the intestinal tube and form the ENS. As these neural progenitors have the daunting task of traveling long distances and bridging ...
Implementation of ratiometric time-lapse fluorescence microscopy for studying metabolic changes in high hydrostatic pressure stressed cells of Escherichia coli O157:H7 KU Leuven
In contrast to (macroscopic) plate count methods, the increased intra- and intercellular resolution provided by current live (microscopic) cell biology approaches allows a much more detailed and online mechanistic dissection of individual cellular behavior in stressed populations of foodborne pathogens, which will become essential to better predict and improve the efficacy of current minimal (non-thermal) processing and preservation practices ...
Disposable sample holder with integrated optics for enabling Light Sheet Microscopy on standard light microscopes Ghent University
The human body is a true wonder. It is composed by an average of A.G trillion cells, subdivided in more than MNN different cell types, each with its function and its own specialization. Yet, life is possible only if those cells manage to communicate and closely collaborate with each other, to reach their common goal. Clearly, collaboration is the key to evolution and progress. This is no different in science. The technological progresses of ...
AQ²UABIT – Advanced Qualitative and QUantitative surface Analysis of BITuminous binders using laser scanning confocal microscopy. University of Antwerp
Stimulated emission depletion microscopy (STED): Nanoscopy for innovative research in the life sciences Ghent University
The well-known adagio ‘seeing is believing’ is as much of relevance to life science research today as it ever was. Since the invention of the first microscopes almost 400 years ago, there has been an ongoing strive to ever see more details within organisms, tissues and cells. Based on fundamental physics from the nineteenth century, it was long thought impossible to see beyond a resolution of ~200 nm with light microscopes. However, thanks to ...