Laboratory of Membrane Trafficking (VIB-KUÂ Leuven) KU Leuven
The research in the Laboratory of Membrane Trafficking is focused on the cell biology and trafficking of the g-secretase components. This multiprotein complex has been implicated in a new signal transduction paradigm, called Regulated Intramembrane Proteolysis or RIP and is critical in a wide variety of important cellular activities including embryogenesis, brain development and haematopoiesis. RIP also plays a central role in Alzheimer's ...