Projects
The Flemish exposome project: towards a comprehensive understanding of the life-course impact of dietary and environmental exposure on chronic low-grade gut inflammation (FLEXiGUT) Ghent University
The human exposome covers the totality of non-genetic exposures from conception throughout the life course. The Flemish exposome project, FLEXiGUT, combines the unique and complementary expertise in Flanders on dietary- and environment-related human biomarkers and biomonitoring, metabolomics, microbiome research and epidemiology to investigate the complex human exposome. This first large-scale Flemish Exposome study, will make use of ...
MYCOGUT: Mycotoxins and gut microbiota, an unresolved interplay towards human chronic low-grade gut inflammation Ghent University
There is an urgent demand to investigate combined effects of multiple mycotoxins over the life course on alterations of the gut microbiota and the development of chronic low-grade gut inflammation through observational studies. Mycotoxins are secondary metabolites produced by toxigenic fungi that contaminate food and feed. Practically everyone undergoes chronic, low-dose, variable dietary exposure to mycotoxins throughout their lives, but ...
The Flemish exposome project: towards a comprehensive understanding of the life-course impact of dietary and environmental exposure on chronic low-grade gut inflammation (FLEXiGUT). University of Antwerp
The Flemish exposome project: towards a comprehensive understanding of the life-course impact of dietary and environmental exposure on chronic low-grade gut inflammation Acronym = FLEXiGUT Hasselt University
Role of mucosal integrity and low-grade inflammation in gastro-oesophageal reflux disease and functional dyspepsia. KU Leuven
Can 3 months strength training counter chronic low-grade inflammation and improve immune function in older persons? Vrije Universiteit Brussel
mediators, defined as a chronic low-grade inflammatory profile
(CLIP) and a reduced skin immunity. Physical exercise is one of the
best means to counter CLIP, and has shown to accelerate wound
healing in older adults. Exercise provokes an acute and brief
liberation of myokines, which induce an anti-inflammatory effect,
probably by ...
The bidirectional stress-obesity relation: mediating role of low-grade inflammation and gut microbiota. Ghent University
Researchers still struggle to understand the complex processes by which psychosocial factors like chronic stress increase disease susceptibility. This project will elucidate mechanistic pathways in the bidirectional stress-obesity relation, i.e. the mediating role of food choice, low-grade inflammation and disturbed gut microbiota. Observational and interventional research will be combined in community samples and clinical samples during ...
ERC connect funding: CLIP-EX: Countering chronic Low-grade Inflammation by Physical Exercise: unraveling muscle–to-immune-cell communication Vrije Universiteit Brussel
Chronic inflammation is present in the elderly population, and is involved in many tissue and cellular dysfunctions with ageing, including the immune system, the skeletal muscle (sarcopenia) or more generally tissue-repair.
Counteracting this chronic inflammation will be beneficial for those age-related dysfunctions, and thus for the general well-being of the aged population.
AIMS
The CLIP-EX project aims at ...