Publications
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Impact of PET reconstruction protocols on quantification of lesions that fulfil the PERCIST lesion inclusion criteria KU Leuven
BACKGROUND: The aim of this study was to compare liver and oncologic lesion standardized uptake values (SUV) obtained through two different reconstruction protocols, GE's newest clinical lesion detection protocol (Q.Clear) and the EANM Research Ltd (EARL) harmonization protocol, and to assess the clinical relevance of potential differences and possible implications for daily clinical practice using the PERCIST lesional inclusion criteria. NEMA ...
Analysis of c-fos and zif268 Expression Reveals Time-Dependent Changes in Activity Inside and Outside the Lesion Projection Zone in Adult Cat Area 17 after Retinal Lesions KU Leuven
Retinal lesions induce a topographic reorganization in the corresponding lesion projection zone (LPZ) in the visual cortex of adult cats. To gain a better insight into the reactivation dynamics, we investigated the alterations in cortical activity throughout area 17. We implemented in situ hybridization and real-time polymerase chain reaction to analyze the spatiotemporal expression patterns of the activity marker genes zif268 and c-fos. The ...
MRI lesions of the spine in patients with axial spondyloarthritis : an update of lesion definitions and validation by the ASAS MRI working group Ghent University Flanders Institute for Biotechnology
Impact of compressed breast thickness and dose on lesion detectability in digital mammography: FROC study with simulated lesions in real mammograms KU Leuven
The aim of this work was twofold: (1) to examine whether, with standard automatic exposure control (AEC) settings that maintain pixel values in the detector constant, lesion detectability in clinical images decreases as a function of breast thickness and (2) to verify whether a new AEC setup can increase lesion detectability at larger breast thicknesses.
Neuronal Patterns in the Cavity Wall of Lesions during Gait Cycle in a Rat Model of Brain Lesion Cavities KU Leuven
Oscillatory neural activity was reported to have various physiological roles in information processing of brain functions. It is now established that extracellular activity in the motor cortex encodes aspects of movement, involving planning and motor control. Oscillatory patterns have also been hypothesized to play a role in brain recovery and functional remapping. In this study, we measured neural activity from within the cavity wall of a motor ...
Immune reactions in benign and malignant melanocytic lesions: lessons for immunotherapy Ghent University
Histopathological Features of MRI-Invisible Regions of Prostate Cancer Lesions KU Leuven
BACKGROUND: Previous studies have reported tumor volume underestimation with multiparametric (mp)MRI in prostate cancer diagnosis. PURPOSE: To investigate why some parts of lesions are not visible on mpMRI by comparing their histopathology features to those of visible regions. STUDY TYPE: Retrospective. POPULATION: Thirty-four patients with biopsy-proven prostate cancer scheduled for prostatectomy (median 68.7 years). FIELD STRENGTH/SEQUENCE: T2 ...