Do shared “omics” biomarkers reveal a systemic pathogenetic condition explaining association between left ventricular dysfunction and macrovascular disease? KU Leuven
Atherosclerosis is the major disease of the macrovasculature and represents the major cause of morbidity and mortality worldwide due to heart attack and stroke. Heart failure (HF) is another syndrome that represents a major public health problem in developing and developed countries alike. A striking observation is that many of the risk factors predicting HF are also related to macrovascular disease. One mechanism that explains this is ...