Publications
Optimal Linear Controller Design for Periodic Inputs and Extended LMI Characterizations for Linear Stability and Performance (Optimaal ontwerp van lineaire regelaars voor periodische ingangssignalen en Karakterisering van lineaire stabiliteit en prestatie KU Leuven
Contributions to the Modeling and Control of Linear Parameter-Varying Systems (Bijdragen tot de modellering en controle van lineaire parameter-variërende systemen) KU Leuven
Comparative genomics of Mycobacterium africanum Lineage 5 and Lineage 6 from Ghana suggests distinct ecological niches Institute of Tropical Medicine
Mycobacterium africanum (Maf) causes a substantial proportion of human tuberculosis in some countries of West Africa, but little is known on this pathogen. We compared the genomes of 253 Maf clinical isolates from Ghana, including N = 175 Lineage 5 (L5) and N = 78 Lineage 6 (L6). We found that the genomic diversity of L6 was higher than in L5 despite the smaller sample size. Regulatory proteins appeared to evolve neutrally in L5 but under ...
Low sensitivity of the MPT64 identification test to detect lineage 5 of the Mycobacterium tuberculosis complex Institute of Tropical Medicine University of Antwerp
Purpose. Differentiation of the Mycobacterium tuberculosis complex (MTBc) from non-tuberculous mycobacteria (NTM) is important for tuberculosis diagnosis and is a prerequisite for reliable phenotypic drug-resistance testing. We evaluated the performance of the rapid MPT64 antigen identification test for the detection of Mycobacterium africanum lineage 5 (MAF L5).
Methodology. Smear-positive tuberculosis patients' sputa were included ...
MEF2C opposes Notch in lymphoid lineage decision and drives leukemia in the thymus Ghent University
Lineage tracing of pancreatic exocrine cell plasticity Vrije Universiteit Brussel
Expressing lineage in Roman and Late Antique petitions and contracts : a variationist perspective Ghent University
A conserved role of the Hippo signalling pathway in initiation of the first lineage specification event across mammals Vrije Universiteit Brussel
Our understanding of the molecular events driving cell specification in early mammalian development relies mainly on mouse studies, and it remains unclear whether these mechanisms are conserved across mammals, including humans. We have shown that the establishment of cell polarity via aPKC is a conserved event in the initiation of the trophectoderm (TE) placental programme in mouse, cow and human embryos. However, the mechanisms transducing ...
Next generation of ALDH substrates and their potential to study maturational lineage biology in stem and progenitor cells Vrije Universiteit Brussel
High aldehyde dehydrogenase (ALDH) activity is a feature of stem cells from normal and cancerous tissues and a reliable universal marker used to isolate them. There are numerous ALDH isoforms with preferred substrate specificity variably expressed depending on tissue, cell type, and organelle and cell status. On the other hand, a given substrate may be metabolized by several enzyme isoforms. Currently ALDH activity is evidenced by using ...