The Royal Decision concerning the eradication of Salmonella in poultry (C U+2013 2007/22784) prohibits prophylactic treatment with antimicrobial drugs; excessive use enlarges the risk of resistance development. The goal of this project is the development and validation of an UPLC-MS/MS method for the quantitative and reliable determination of residues of antimicrobials in non-invasive samples (chicken manure).
This project will perform an exposure assessment for mycotoxins in Belgium by direct measurements of biomarkers of exposure in morning urine of a representative part of the Belgian population using a validated LC-MS/MS method. Correlations between mycotoxin concentrations measured and the foods consumption reported of both the day before the urine collection and the previous month, will be estimated.
Monitoring of the presence of brominated flame retardants in foodstuffs (FLAREFOOD) University of Antwerp
The primary objective of the project is to respond to the EU draft regulation on the monitoring of BFRs in food. Indeed, there is a lack of information on the occurrence data of BFRs in food which has hampered an accurate completion of intake assessment by EFSA. Firstly, two analytical methods will be developed and validated. Due to the diverse nature of various BFRs which need to be included, a GC-MS and a LC-MSMS method needs to be developed. ...
MYCOMASK: Assessment of the chemical risk associated with masked Fusarium toxin-containing foodstuffs Ghent University
Masked mycotoxins, in which the toxin is usually bound to a more polar substance such as glucose, escape established analytical techniques. Little is known about the occurrence of these compounds in foodstuffs. In this project, a liquid chromatography tandem mass spectrometry (LC-MS/MS) method that allows the simultaneous determination of free and masked mycotoxins will be developed and applied to a survey on the occurrence of masked ...
Presence of chlorinated paraffins in foodstuffs and intake of the Belgian population. University of Antwerp
Chlorinated paraffins (CPs), also known as polychlorinated n-alkanes with chlorine degree ranging from 30% to 70% by mass, are a complex mixture of thousands of isomers, diastereomers, and enantiomers. They can be divided into short (SCCPs, C10-C13), medium (MCCPs, C14-17), and long chain CPs (LCCPs, > C17) according to their carbon chain length. Among all CP groups, SCCPs have the highest toxic potential. Although it has been ...
Sensitive GC-MS / MS method, Development and validation of a sensitive GC-MS / MS method for doping agents. Flemish Government - Ministry of Finance, Budget, Work and Sport
We will develop a multi-analyte approach (HPLC-MS/MS) to measure the exposure to the mycotoxins based on developed biomarkers of different mycotoxins from urine samples. We will develop a fast and reliable clean-up method (salt out assisted liquid-liquid extraction) to circumvent the influence of the urine matrix. After validation, we will apply it to human and pig urine.