A model based rehabilitation protocol after cartilage lesions based on mechanical loading of the knee joint. KU Leuven
Articular cartilage defects of the knee joint are commonly caused by trauma during sports activities. Cartilage has low self-repair and regenerative capabilities, partially due to its avascular nature, the low intrinsic density of chondrocytes, and the low turnover of the extracellular matrix. If left untreated, cartilage injuries are a major risk factor for further cartilage degeneration and eventually osteoarthritis. Therefore, the ability ...