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Disease severity in patients with visceral leishmaniasis is not altered by co-infection with intestinal parasites Hasselt University

Fitsumbrhan Tajebe, Mulusew Getahun, Emebet Adem, Asrat Hailu, Mulualem Lemma, Helina Fikre, John Raynes, Aschalew Tamiru, Zemenay Mulugeta, Ermias Diro, et al.
Visceral leishmaniasis (VL) is a neglected tropical disease that affects the poorest communities and can cause substantial morbidity and mortality. Visceral leishmaniasis is characterized by the presence of Leishmania parasites in the spleen, liver and bone marrow, hepatosplenomegaly, pancytopenia, prolonged fever, systemic inflammation and low body mass index (BMI). The factors impacting on the severity of VL are poorly characterized. Here we ...

Field evaluation of a topical doramectin formulation for the chemoprophylaxis of parasitic bronchitis in calves Institute of Tropical Medicine

J. Vercruysse, Pierre Dorny, E Claerebout, A Weatherley

A study was conducted to evaluate the efficacy of two topical treatments with doramectin on the season-long control of lungworm and gastrointestinal infections in first grazing season (FGS) calves. At the start of the study, 20 FGS calves were randomly allocated into two treatment groups of 10 animals each. Calves in the D-group were treated with doramectin pour-on on days 0 and 56, at a dosage of 500 microg kg(-1) BW: calves in the C-group ...

The burden of parasitic zoonoses in Nepal Institute of Tropical Medicine Ghent University

Brecht Devleesschauwer, Anita Ale, Paul Torgerson, Nicolas Praet, Charline Maertens de Noordhout, Basu Dev Pandey, Sher Bahadur Pun, Rob Lake, Jozef Vercruysse, Durga Datt Joshi, et al.

BACKGROUND: Parasitic zoonoses (PZs) pose a significant but often neglected threat to public health, especially in developing countries. In order to obtain a better understanding of their health impact, summary measures of population health may be calculated, such as the Disability-Adjusted Life Year (DALY). However, the data required to calculate such measures are often not readily available for these diseases, which may lead to a vicious ...

Are intestinal parasites fuelling the rise in dual burden households in Venezuela? Institute of Tropical Medicine

M. Campos Ponce, R.N. Incani, E. Pinelli, N. ten Kulve, R. Ramak, Katja Polman, C.M. Doak
BACKGROUND: In developing countries undergoing rapid economic development, the number of dual burden households (i.e. co-existing overweight/obesity and stunting) is increasing. While intestinal parasites are prevalent in these countries, their contribution to dual burden households has so far been neglected. We studied the association between intestinal parasite infection and belonging to a dual burden household in a rural community of ...

Giardia and other intestinal parasites in different dog populations in Northern Belgium. Royal Zoological Society of Antwerp Ghent University

E. Claerebout, S. Casaert, a-C Dalemans, N De Wilde, Bruno Levecke, J. Vercruysse, T Geurden
The objectives of this study were to obtain data on the prevalence of intestinal parasites in different dog populations in northern Belgium, to estimate the zoonotic risk associated with these infections and to identify potential risk factors. Between 2004 and 2007 a total of 1159 faecal samples were collected from 451 household dogs, 357 dogs from breeding kennels and 351 dogs with gastrointestinal disorders. The samples from dogs with ...

The intestinal expulsion of the roundworm Ascaris suum is associated with eosinophils, intra-epithelial T cells and decreased intestinal transit time Ghent University

Dries Masure, Tao Wang, Johnny Vlaminck, Sarah Claerhoudt, Koen Chiers, Wim Van Den Broeck, Jimmy Saunders, Jozef Vercruysse, Peter Geldhof
Ascaris lumbricoides remains the most common endoparasite in humans, yet there is still very little information available about the immunological principles of protection, especially those directed against larval stages. Due to the natural host-parasite relationship, pigs infected with A. suum make an excellent model to study the mechanisms of protection against this nematode. In pigs, a self-cure reaction eliminates most larvae from the small ...