Study of the role of MAGED1 in the ubiquitylation-dependent regulation of the inflammatory response Ghent University
The proposed research project aims at revealing and characterizing the physiological role of MAGED1, a member of the enigmatic melanoma antigen gene (MAGE) family, in the regulation of the inflammatory response. Ubiquitylation plays crucial roles in activating and limiting various levels of innate immune and inflammatory pathways, and several lines of evidence (including preliminary data) indicate that MAGED1 could regulate inflammation by ...