The microbiome in colorectal metastases: nature and impact on local immune and inflammatory response, disease evolution and response to therapy KU Leuven
Despite evidence associating colorectal cancer (CRC) and microbiome, its role in metastatic CRC remains
unexplored. In this project, we aim to characterize bacterial colonization of CRC metastases matched with
primary tumors, surrounding normal tissues and evaluate its relationship with tumor characteristics, including
molecular subtype, pattern of histological growth, local immune response and alteration in T-cell antigen ...