Gnotobiotic Artemia brine shrimp as a model for studying the transcriptional, translational and epigenetic mechanisms responsible for immune 'imprinting' against infectious diseases in invertebrates Ghent University
Invertebrates, including shrimps, rely on their innate immunity to fight against pathogens. Innate immunity lacks the ability to show high degree of specificity and long-lasting memory. However, few reports claimed that invertebrates show some form of immunological specificity and memory similar to that of adaptive immunity in vertebrates. Using the gnotobiotic brine shrimp Artemia as model organism, this project aims to unambiguously prove ...
Innate imprinting of resident alveolar macrophages by allergic airway inflammation: mechanism and consequences for asthma exacerbation Ghent University
In a mouse model of asthma, resident alveolar macrophages showed an increased inflammatory reactivity upon post-infection of the asthmatic lung. This project aims to elucidate the mechanism underlying the altered macrophage innate functionality and hereby to enable interference with asthma exacerbation.
Analytical separations of complex samples using novel affinity matrices based on molecularly imprinted polymers Hasselt University
Design and development of molecular imprinted polymers with high affinity to the template based on one building block. Hasselt University
New advanced passive photonic components will be fabricated in polymer using the nano-imprint technique. The components include a.o. microring resonators with high Q factor for sensing, athermal SOI microring resonators on the basis of slot waveguides with polymer overlay and triplexers based on asymmetric Y-junctions for use in FTTH
Molecularly imprinted polymers as a clean-up technique for T-2 toxin, HT-2 toxin and patulin in complex food matrices Ghent University
The general procedures to trace food contaminants consists of 3 steps: extraction, clean-up and a detection/quantification step. Regarding the first steps immunoaffinity columns exhibit excellent selectivity, but this technique has many disadvantages (expensive, not reusable, U+2026). The purpose of this project is to develop molecularly imprinted polymers applicable for T-2, HT-2 and patulin as an alternative for immunoaffinity columns.