Tricking tumor immunosuppression: RNA epigenetics as novel target to improve cancer immunotherapy KU Leuven
Immunotherapy is considered as a major breakthrough in the treatment of cancer, but still a large fraction of
the patients are not responsive and several cancer types are refractory to this therapy. The presence of a
strongly immune suppressive environment within primary tumors and at the metastatic site is a likely explanation for the suboptimal efficacy of immunotherapy, with tumor-associated macrophages (TAMs) and ...